BDBM50300592 CHEMBL573964::N-(1-methyl-1H-pyrazol-3-yl)-6-(4-methyl-2-(methylsulfonyl)phenoxy)quinazolin-4-amine

SMILES Cc1ccc(Oc2ccc3ncnc(Nc4ccn(C)n4)c3c2)c(c1)S(C)(=O)=O

InChI Key InChIKey=UXSQYXDWUHUHEM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300592   

TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50300592(N-(1-methyl-1H-pyrazol-3-yl)-6-(4-methyl-2-(methyl...)
Affinity DataEC50:  570nMAssay Description:Activation of N-terminal His-tagged human recombinant liver glucokinase expressed in Escherichia coli BL21 (DE3) by glucose-6-phosphate dehydrogenase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50300592(N-(1-methyl-1H-pyrazol-3-yl)-6-(4-methyl-2-(methyl...)
Affinity DataEC50:  5.10E+3nMAssay Description:Activation of N-terminal His-tagged human recombinant liver glucokinase expressed in Escherichia coli BL21 (DE3) by glucose-6-phosphate dehydrogenase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed