BDBM50300611 4-methyl-N-(6-(4-methyl-4H-1,2,4-triazol-3-ylthio)quinazolin-4-yl)thiazol-2-amine::CHEMBL575903

SMILES Cc1csc(Nc2ncnc3ccc(Sc4nncn4C)cc23)n1

InChI Key InChIKey=DPRXXHHICPMXGX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300611   

TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50300611(4-methyl-N-(6-(4-methyl-4H-1,2,4-triazol-3-ylthio)...)
Affinity DataEC50:  920nMAssay Description:Activation of N-terminal His-tagged human recombinant liver glucokinase expressed in Escherichia coli BL21 (DE3) by glucose-6-phosphate dehydrogenase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50300611(4-methyl-N-(6-(4-methyl-4H-1,2,4-triazol-3-ylthio)...)
Affinity DataEC50:  2.10E+3nMAssay Description:Activation of N-terminal His-tagged human recombinant liver glucokinase expressed in Escherichia coli BL21 (DE3) by glucose-6-phosphate dehydrogenase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed