BDBM50300716 8-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-8-(3-(2-fluoropyridin-3-yl)phenyl)-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine::CHEMBL566969

SMILES NC1=NC(C2=NCCCN12)(c1ccc2OC(F)(F)Oc2c1)c1cccc(c1)-c1cccnc1F

InChI Key InChIKey=MMUYGEDDWAWBAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300716   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300716(8-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-8-(3-(2-f...)
Affinity DataIC50: 740nMAssay Description:Inhibition of human BACE1 by FRETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300716(8-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-8-(3-(2-f...)
Affinity DataIC50: 9.53E+4nMAssay Description:Inhibition of human cathepsin D by FRETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed