BDBM50300838 CHEMBL565552::N,N-Dimethyl-N-{2-[3-(1-naphthylsulfonyl)-1Hpyrrolo[2,3-b]pyridin-1-yl]ethyl}amine

SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=NSQFNGCVKOBFOP-UHFFFAOYSA-N

Data  1 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50300838   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(N,N-Dimethyl-N-{2-[3-(1-naphthylsulfonyl)-1Hpyrrol...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(N,N-Dimethyl-N-{2-[3-(1-naphthylsulfonyl)-1Hpyrrol...)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as induction of adenylyl cyclase activity by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(N,N-Dimethyl-N-{2-[3-(1-naphthylsulfonyl)-1Hpyrrol...)
Affinity DataIC50: 511nMAssay Description:Displacement of [3H]LSD from human cloned 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(N,N-Dimethyl-N-{2-[3-(1-naphthylsulfonyl)-1Hpyrrol...)
Affinity DataIC50: 938nMAssay Description:Displacement of [125I]DOI from human cloned 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(N,N-Dimethyl-N-{2-[3-(1-naphthylsulfonyl)-1Hpyrrol...)
Affinity DataIC50: 1.14E+3nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(N,N-Dimethyl-N-{2-[3-(1-naphthylsulfonyl)-1Hpyrrol...)
Affinity DataIC50: 1.56E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(N,N-Dimethyl-N-{2-[3-(1-naphthylsulfonyl)-1Hpyrrol...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed