BDBM50300845 CHEMBL565746::N-(2-{3-[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethyl)-Nmethylamine

SMILES CNCCn1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12

InChI Key InChIKey=CTYXKOVPFGUJOK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300845   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300845(N-(2-{3-[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300845(N-(2-{3-[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)...)
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as inhibition of adenylyl cyclase activity by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed