BDBM50300995 (2S,3R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-olHydrochloride::CHEMBL565309::CHEMBL567041

SMILES CNC[C@H](O)[C@@H](c1ccccc1)n1ccc2ccccc12

InChI Key InChIKey=ANOKEIWYHCYLAM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50300995   

TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300995(CHEMBL565309 | CHEMBL567041 | (2S,3R)-1-(1H-indol-...)
Affinity DataIC50: 74nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300995(CHEMBL565309 | CHEMBL567041 | (2S,3R)-1-(1H-indol-...)
Affinity DataIC50: 79nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300995(CHEMBL565309 | CHEMBL567041 | (2S,3R)-1-(1H-indol-...)
Affinity DataIC50: 104nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300995(CHEMBL565309 | CHEMBL567041 | (2S,3R)-1-(1H-indol-...)
Affinity DataIC50: 144nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed