BDBM50301013 4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-((4-methylpiperazin-1-yl)methyl)pyridin-2-yl)quinoline-3-carbonitrile::CHEMBL567875

SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCN(C)CC3)cn2)C#N)c(Cl)cc1Cl

InChI Key InChIKey=XRDHKNJEMDHMPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301013   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301013(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-((4-met...)
Affinity DataIC50: 4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301013(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-((4-met...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed