BDBM50301016 4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1,1-dioxo-1lambda*6*-thiomorpholin-4-ylmethyl)-pyridin-2-yl]quinoline-3-carbonitrile::CHEMBL585198

SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCS(=O)(=O)CC3)cn2)C#N)c(Cl)cc1Cl

InChI Key InChIKey=YKKNMIJDQNMCHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301016   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301016(4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1,1-d...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301016(4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1,1-d...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed