BDBM50301019 4-(2,4-dichlorophenylamino)-7-(5-((4-methylpiperazin-1-yl)methyl)pyridin-2-yl)quinoline-3-carbonitrile::CHEMBL567230

SMILES CN1CCN(Cc2ccc(nc2)-c2ccc3c(Nc4ccc(Cl)cc4Cl)c(cnc3c2)C#N)CC1

InChI Key InChIKey=PUPJNCZQOQCZBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301019   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301019(4-(2,4-dichlorophenylamino)-7-(5-((4-methylpiperaz...)
Affinity DataIC50: 12nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301019(4-(2,4-dichlorophenylamino)-7-(5-((4-methylpiperaz...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed