BDBM50301216 4-(5-methoxy-1-(4-(trifluoromethyl)benzyl)-2,3,3a,7a-tetrahydro-1H-inden-1-yl)-1-methyl-1H-imidazol-2-amine::CHEMBL566463

SMILES COC1=CC2CCC(Cc3ccc(cc3)C(F)(F)F)(C2C=C1)c1cn(C)c(N)n1

InChI Key InChIKey=FDWHRNRDGMYDCB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301216   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301216(4-(5-methoxy-1-(4-(trifluoromethyl)benzyl)-2,3,3a,...)
Affinity DataIC50: 350nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed