BDBM50301287 2-benzyl-1-methyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepin-3(4H)-one::CHEMBL576912

SMILES Cn1c2CCNCCc2c(=O)n1Cc1ccccc1

InChI Key InChIKey=UMCHVGPMZOXWPI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301287   

Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301287(2-benzyl-1-methyl-1,2,5,6,7,8-hexahydropyrazolo[4,...)
Affinity DataEC50:  2.93E+3nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301287(2-benzyl-1-methyl-1,2,5,6,7,8-hexahydropyrazolo[4,...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed