BDBM50301919 4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hydroxyphenyl)cyclohexyl)methyl)(methyl)amino)ethyl)-2-methoxybenzamide::CHEMBL569357

SMILES COc1cc(N)c(Cl)cc1C(=O)NCCN(C)C[C@H]1CCCC[C@]1(O)c1cccc(O)c1

InChI Key InChIKey=HFOUMBDMIJJHCK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50301919   

TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 190nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 340nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed