BDBM50301987 2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluoro-4-(methylamino)pyridin-2-yloxy)-4-(dimethylamino)benzoic acid::CHEMBL569560

SMILES CNc1c(F)c(Oc2cccc(c2)-c2cccc(CN)c2)nc(Oc2cc(ccc2C(O)=O)N(C)C)c1F

InChI Key InChIKey=AZHDSUBGWFZIMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301987   

TargetUrokinase-type plasminogen activator(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301987(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50: 130nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301987(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301987(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed