BDBM50302061 6-((2S,5S,8S,11S)-2-benzyl-11-isobutyl-8-(naphthalen-1-ylmethyl)-3,6,9,13-tetraoxo-1,4,7,10-tetraazacyclotridecan-5-yl)hexanoic acid::CHEMBL569211

SMILES CC(C)C[C@H]1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCCCC(O)=O)C(=O)N[C@@H](Cc2cccc3ccccc23)C(=O)N1

InChI Key InChIKey=WEUKJQCIVIFTNN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302061   

TargetHistone deacetylase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302061(6-((2S,5S,8S,11S)-2-benzyl-11-isobutyl-8-(naphthal...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302061(6-((2S,5S,8S,11S)-2-benzyl-11-isobutyl-8-(naphthal...)
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302061(6-((2S,5S,8S,11S)-2-benzyl-11-isobutyl-8-(naphthal...)
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant HDAC3 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302061(6-((2S,5S,8S,11S)-2-benzyl-11-isobutyl-8-(naphthal...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed