BDBM50302073 6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benzyl-11-isobutyl-3,6,9,13-tetraoxo-1,4,7,10-tetraazacyclotridecan-5-yl)-N-hydroxyhexanamide::CHEMBL566637

SMILES CC(C)C[C@H]1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCCCC(=O)NO)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N1

InChI Key InChIKey=ADVAWAGNRHNMPQ-ABYARXGNSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50302073   

LigandPNGBDBM50302073(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benz...)
Affinity DataIC50:  31nMAssay Description:Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302073(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benz...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302073(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benz...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant HDAC3 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302073(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benz...)
Affinity DataIC50:  70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302073(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benz...)
Affinity DataIC50:  70nMAssay Description:Inhibition of HDAC6 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302073(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benz...)
Affinity DataIC50:  31nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50302073(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benz...)
Affinity DataIC50:  8nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed