BDBM50302268 CHEMBL578206::N-((R)-4-(3,4-dimethoxyphenyl)-4-(1-oxo-4-(4-((R)-1-phenylethyl)piperazin-1-yl)isoindolin-2-yl)butyl)-5-methylisoxazole-4-carboxamide
SMILES COc1ccc(cc1OC)[C@@H](CCCNC(=O)c1cnoc1C)N1Cc2c(cccc2N2CCN(CC2)[C@H](C)c2ccccc2)C1=O
InChI Key InChIKey=WYGHIDQLPZLSFF-NLGDKJDOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50302268
TargetUrotensin-2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [125I]urotensin 2 from urotensin 2 receptor in human RMS13 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetUrotensin-2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Antagonist activity at urotensin 2 receptor in human RMS13 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization aft...More data for this Ligand-Target Pair
TargetUrotensin-2 receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...More data for this Ligand-Target Pair