BDBM50302430 2-(9-(2-hydroxy-2-methylpropyl)-6-isobutoxy-1H-phenanthro[9,10-d]imidazol-2-yl)isophthalonitrile::CHEMBL565617

SMILES CC(C)COc1ccc2c3[nH]c(nc3c3ccc(CC(C)(C)O)cc3c2c1)-c1c(cccc1C#N)C#N

InChI Key InChIKey=VGJUAMQHMGNVNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302430   

TargetProstaglandin E synthase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302430(2-(9-(2-hydroxy-2-methylpropyl)-6-isobutoxy-1H-phe...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed