BDBM50302469 CHEMBL568544::N-(2-chloro-4-(methylsulfonyl)benzyl)-6-(3,3,3-trifluoropropoxy)nicotinamide

SMILES CS(=O)(=O)c1ccc(CNC(=O)c2ccc(OCCC(F)(F)F)nc2)c(Cl)c1

InChI Key InChIKey=XFGSFBYQEMRAIB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302469   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302469(N-(2-chloro-4-(methylsulfonyl)benzyl)-6-(3,3,3-tri...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human soluble EHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302469(N-(2-chloro-4-(methylsulfonyl)benzyl)-6-(3,3,3-tri...)
Affinity DataIC50: 16nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302469(N-(2-chloro-4-(methylsulfonyl)benzyl)-6-(3,3,3-tri...)
Affinity DataIC50: 28nMAssay Description:Inhibition of soluble EH in human HepG2 cells by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed