BDBM50302474 CHEMBL572205::N-(2,4-dichlorobenzyl)-6-(2,2,2-trifluoroethoxy)nicotinamide

SMILES FC(F)(F)COc1ccc(cn1)C(=O)NCc1ccc(Cl)cc1Cl

InChI Key InChIKey=CQQHCCHCAFBVMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302474   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302474(N-(2,4-dichlorobenzyl)-6-(2,2,2-trifluoroethoxy)ni...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human soluble EHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302474(N-(2,4-dichlorobenzyl)-6-(2,2,2-trifluoroethoxy)ni...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302474(N-(2,4-dichlorobenzyl)-6-(2,2,2-trifluoroethoxy)ni...)
Affinity DataIC50: 18nMAssay Description:Inhibition of soluble EH in human HepG2 cells by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed