BDBM50303130 CHEMBL585148::Methyl 6-(4-chloro-3-hydroxyphenyl)-15-methyl-5-(pyridin-4-yl)-3,4,8,15-tetraazatetracyclo[10.2.1.0^{2,10}.0^{3,7}]pentadeca-2(10),4,6,8-tetraene-13-carboxylate

SMILES COC(=O)C1CC2N(C)C1Cc1cnc3c(c(nn3c21)-c1ccncc1)-c1ccc(Cl)c(O)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50303130   

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303130(Methyl 6-(4-chloro-3-hydroxyphenyl)-15-methyl-5-(p...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed