BDBM50303265 CHEMBL566003::N1-(3-fluoro-4-(2-(1-methyl-1H-imidazole-4-carbonyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamide

SMILES Cn1cnc(c1)C(=O)c1cc2nccc(Oc3ccc(NC(=O)CC(=O)Nc4ccccc4)cc3F)c2s1

InChI Key InChIKey=SUYDWRHGHAJQHG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303265   

TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50303265(N1-(3-fluoro-4-(2-(1-methyl-1H-imidazole-4-carbony...)
Affinity DataIC50: 25nMAssay Description:Inhibition of GST-fused recombinant C-met expressed in baculovirus infected high five cells after 30 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50303265(N1-(3-fluoro-4-(2-(1-methyl-1H-imidazole-4-carbony...)
Affinity DataIC50: 30nMAssay Description:Inhibition of GST-fused recombinant VEGFR2 expressed in baculovirus infected Sf9 cells after 10 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50303265(N1-(3-fluoro-4-(2-(1-methyl-1H-imidazole-4-carbony...)
Affinity DataIC50: 340nMAssay Description:Inhibition of TPR-met autophosphorylation expressed in HEK293T cells after 150 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed