BDBM50303710 CHEMBL566643::N-{(E)-3-[1-(3,5-Dimethylisoxazol-4-ylmethyl)-5-fluoro-3-methyl-1H-indol-7-yl]acryloyl}-3,4-difluorobenzenesulfonamide

SMILES Cc1cn(Cc2c(C)noc2C)c2c(\C=C\C(=O)NS(=O)(=O)c3ccc(F)c(F)c3)cc(F)cc12

InChI Key InChIKey=ZERUZZSPUFDMCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303710   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303710(N-{(E)-3-[1-(3,5-Dimethylisoxazol-4-ylmethyl)-5-fl...)
Affinity DataIC50: 14.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303710(N-{(E)-3-[1-(3,5-Dimethylisoxazol-4-ylmethyl)-5-fl...)
Affinity DataIC50: 4.79E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed