BDBM50303740 2-amino-4-(3-methoxyphenyl)-1-methyl-4-phenyl-1H-imidazol-5(4H)-one::CHEMBL576628

SMILES COc1cccc(c1)C1(N=C(N)N(C)C1=O)c1ccccc1

InChI Key InChIKey=BNTCTQFWBJMVDZ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303740   

TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303740(2-amino-4-(3-methoxyphenyl)-1-methyl-4-phenyl-1H-i...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human BACE2 by FRET based peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303740(2-amino-4-(3-methoxyphenyl)-1-methyl-4-phenyl-1H-i...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303740(2-amino-4-(3-methoxyphenyl)-1-methyl-4-phenyl-1H-i...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of human BACE1 by FRET based peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303740(2-amino-4-(3-methoxyphenyl)-1-methyl-4-phenyl-1H-i...)
Affinity DataEC50:  5.90E+3nMAssay Description:Inhibition of BACE1 expressed in CHOK1 cells coexpressing human recombinant wild type APP assessed as blockade of amyloid beta production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed