BDBM50303931 4-(dimethylamino)naphthalen-1-ol::CHEMBL571241

SMILES CN(C)c1ccc(O)c2ccccc12

InChI Key InChIKey=QTXDOZVNRMLLPN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303931   

TargetHistone acetyltransferase p300(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50303931(4-(dimethylamino)naphthalen-1-ol | CHEMBL571241)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of KAT3B catalytic domain (1284 to 1673 residues) (unknown origin) using SGRGKGGKGLGKGGAKRHRK-NH2 as substrate after 5 mins in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50303931(4-(dimethylamino)naphthalen-1-ol | CHEMBL571241)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of KAT2B catalytic domain (492 to 658 residues) (unknown origin) using H-ARTKQTARKSTGGKAPRKQL-OH as substrate after 5 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT8(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50303931(4-(dimethylamino)naphthalen-1-ol | CHEMBL571241)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using SGRGK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303931(4-(dimethylamino)naphthalen-1-ol | CHEMBL571241)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed