BDBM50304045 CHEMBL608703::methyl 3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C
InChI Key InChIKey=ZEOHVQFWFVMPGM-JYVUQVBGSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50304045
Affinity DataKi: 2.70nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [125I]-IPT from DAT transfected in pig LLC-PK1 cells by radioligand competition binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University
Curated by ChEMBL
Aarhus University
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant SERT expressed in african gree...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Aarhus University
Curated by ChEMBL
Aarhus University
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant NET expressed in african green...More data for this Ligand-Target Pair