BDBM50304101 (RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-yl)-propanoic acid::CHEMBL611036

SMILES NC(Cc1cc(Cl)c(Cl)c(c1)-c1cccc(O)c1)C(O)=O

InChI Key InChIKey=ZNFSSBKROKSXNN-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50304101   

TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  5.03E+3nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  1.71E+4nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA1o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  5.23E+4nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK3A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  5.51E+4nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA3o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  7.81E+4nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK2(V,C,R)A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  9.23E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR5-1b expressed in baculovirus-infected insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed