BDBM50304215 CHEMBL593770::N-[4-(6''-Chlorobenzo[d]thiazol-2''-yl)-2-fluorophenyl]-6'-methoxy-7'-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4'-amine

SMILES COc1cc(ccc1-c1nc2ccccc2s1)N(C)c1ncnc2cc(OCCCN3CCN(C)CC3)c(OC)cc12

InChI Key InChIKey=NSXLLHJZQNFGCH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50304215   

TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304215BDBM50304215(N-[4-(6''-Chlorobenzo[d]thiazol-2''-yl)-2-fluoroph...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304215BDBM50304215(N-[4-(6''-Chlorobenzo[d]thiazol-2''-yl)-2-fluoroph...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304215BDBM50304215(N-[4-(6''-Chlorobenzo[d]thiazol-2''-yl)-2-fluoroph...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304215BDBM50304215(N-[4-(6''-Chlorobenzo[d]thiazol-2''-yl)-2-fluoroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50304215BDBM50304215(N-[4-(6''-Chlorobenzo[d]thiazol-2''-yl)-2-fluoroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbeta by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50304215BDBM50304215(N-[4-(6''-Chlorobenzo[d]thiazol-2''-yl)-2-fluoroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50304215BDBM50304215(N-[4-(6''-Chlorobenzo[d]thiazol-2''-yl)-2-fluoroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR3 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed