BDBM50304418 CHEMBL596394::cis-4-(3,4-Dimethoxyphenyl)-2-[3-(morpholinomethyl)benzyl]-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
SMILES COc1ccc(cc1OC)C1=NN(Cc2cccc(CN3CCOCC3)c2)C(=O)[C@@H]2CC=CC[C@H]12
InChI Key InChIKey=APJGHPHCHXMDTK-BJKOFHAPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50304418
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550
Curated by ChEMBL
Kyoto 601-8550
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair