BDBM50304420 6-(3,4-Dimethoxyphenyl)-2-[4-(morpholinomethyl)benzyl]-4,5-dihydropyridazin-3(2H)-one::CHEMBL592942

SMILES COc1ccc(cc1OC)C1=NN(Cc2ccc(CN3CCOCC3)cc2)C(=O)CC1

InChI Key InChIKey=DDTKYSISTKVJJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304420   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304420(6-(3,4-Dimethoxyphenyl)-2-[4-(morpholinomethyl)ben...)
Affinity DataIC50: 45.9nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed