BDBM50304663 CHEMBL595040::ethyl 2-(3-chlorobenzyl)-5-hydroxy-8-phenyl-1H-benzo[g]indole-3-carboxylate

SMILES CCOC(=O)c1c(Cc2cccc(Cl)c2)[nH]c2c1cc(O)c1ccc(cc21)-c1ccccc1

InChI Key InChIKey=DNIHSBAQPIXVFK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304663   

TargetProstaglandin E synthase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50304663(ethyl 2-(3-chlorobenzyl)-5-hydroxy-8-phenyl-1H-ben...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of mPGES1 in IL1-beta induced human A549 cell microsomal membrane assessed as blockade of conversion of PGH2 to PGE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed