BDBM50304664 CHEMBL605093::ethyl 1-(biphenyl-4-yl)-2-(3-chlorobenzyl)-5-hydroxy-1H-indole-3-carboxylate

SMILES CCOC(=O)c1c(Cc2cccc(Cl)c2)n(-c2ccc(cc2)-c2ccccc2)c2ccc(O)cc12

InChI Key InChIKey=AQLIJDZJAUVNPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304664   

TargetProstaglandin E synthase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50304664(ethyl 1-(biphenyl-4-yl)-2-(3-chlorobenzyl)-5-hydro...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of mPGES1 in IL1-beta induced human A549 cell microsomal membrane assessed as blockade of conversion of PGH2 to PGE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed