BDBM50304668 CHEMBL605915::methyl 4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenylcarbamate

SMILES COC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2sccc2n1

InChI Key InChIKey=HOVHLAZIOZBMAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304668   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304668(methyl 4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)t...)
Affinity DataIC50: 11nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304668(methyl 4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)t...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed