BDBM50304683 5-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine::CHEMBL603212

SMILES Nc1ncc(cn1)-c1nc(N2CC3CCC(C2)O3)c2sccc2n1

InChI Key InChIKey=RQUSSQSOEJOAEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304683   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304683(5-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50: 57nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304683(5-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50: 246nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed