BDBM50304687 3-(2-(1H-indol-5-yl)thieno[3,2-d]pyrimidin-4-yl)-8-oxa-3-azabicyclo[3.2.1]octane::CHEMBL593186

SMILES C1CC2CN(CC1O2)c1nc(nc2ccsc12)-c1ccc2[nH]ccc2c1

InChI Key InChIKey=XGYOLCHTMBWRGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304687   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304687(3-(2-(1H-indol-5-yl)thieno[3,2-d]pyrimidin-4-yl)-8...)
Affinity DataIC50: 22nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304687(3-(2-(1H-indol-5-yl)thieno[3,2-d]pyrimidin-4-yl)-8...)
Affinity DataIC50: 8.62E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed