BDBM50304940 CHEMBL591573::N-phenethyl-4-(4-(2-(trifluoromethyl)benzoyl)piperazin-1-yl)benzamide

SMILES FC(F)(F)c1ccccc1C(=O)N1CCN(CC1)c1ccc(cc1)C(=O)NCCc1ccccc1

InChI Key InChIKey=MICGRTLHXGYMDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304940   

TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304940(N-phenethyl-4-(4-(2-(trifluoromethyl)benzoyl)piper...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304940(N-phenethyl-4-(4-(2-(trifluoromethyl)benzoyl)piper...)
Affinity DataIC50: 820nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed