BDBM50305299 3-(6-morpholino-9H-purin-2-yl)phenol::CHEMBL593515

SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2[nH]cnc2n1

InChI Key InChIKey=FUDQNOGEMXSUSQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50305299   

LigandPNGBDBM50305299(3-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59351...)
Affinity DataIC50: 150nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50305299(3-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59351...)
Affinity DataIC50: 232nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305299(3-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59351...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50305299(3-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59351...)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50305299(3-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59351...)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305299(3-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59351...)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed