BDBM50305305 3-(9-(1-((6-methoxypyridin-3-yl)methyl)piperidin-4-yl)-6-morpholino-9H-purin-2-yl)phenol::CHEMBL591807

SMILES COc1ccc(CN2CCC(CC2)n2cnc3c(nc(nc23)-c2cccc(O)c2)N2CCOCC2)cn1

InChI Key InChIKey=OEKPVDAQJATZGK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305305   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305305(3-(9-(1-((6-methoxypyridin-3-yl)methyl)piperidin-4...)
Affinity DataIC50: 51nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50305305(3-(9-(1-((6-methoxypyridin-3-yl)methyl)piperidin-4...)
Affinity DataIC50: 55nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50305305(3-(9-(1-((6-methoxypyridin-3-yl)methyl)piperidin-4...)
Affinity DataIC50: 306nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed