BDBM50305374 3-(3,4-Dimethoxy-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone::CHEMBL600762

SMILES COc1ccc(\C=C\C(=O)n2nc(C)c3[C@H]4[C@@H](Cc23)C4(C)C)cc1OC

InChI Key InChIKey=VUKYWEMGKPJSJA-IVYBTYKASA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50305374   

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305374(3-(3,4-Dimethoxy-phenyl)-1-((3bS,4aR)-3,4,4-trimet...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human SIP1 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305374(3-(3,4-Dimethoxy-phenyl)-1-((3bS,4aR)-3,4,4-trimet...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human SIP5 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305374(3-(3,4-Dimethoxy-phenyl)-1-((3bS,4aR)-3,4,4-trimet...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human SIP4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305374(3-(3,4-Dimethoxy-phenyl)-1-((3bS,4aR)-3,4,4-trimet...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human SIP3 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed