BDBM50305375 3-(2-Chloro-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone::CHEMBL591102

SMILES Cc1nn(C(=O)\C=C\c2ccccc2Cl)c2C[C@@H]3[C@H](c12)C3(C)C

InChI Key InChIKey=PKXVBXQWZXYOGL-XCUIMDOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50305375   

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305375(3-(2-Chloro-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human SIP1 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305375(3-(2-Chloro-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human SIP5 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305375(3-(2-Chloro-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human SIP4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305375(3-(2-Chloro-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human SIP3 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed