BDBM50305390 2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-((R)-3-(4-fluorobenzyloxy)pyrrolidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile::CHEMBL604456

SMILES Fc1ccc(CO[C@@H]2CCN(C2)C(=O)c2nn(c(c2CC#N)-c2ccc(Cl)cc2)-c2ccccc2Cl)cc1

InChI Key InChIKey=XXSLJISEFOLKBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305390   

TargetCannabinoid receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50305390(2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-((R)-3-...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed