BDBM50305442 (R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-propionamidobutyl)-N-((S)-1-cyclohexyl-3-(methylamino)propan-2-yl)piperidine-1-carboxamide::CHEMBL604248

SMILES CCC(=O)NCCC[C@](O)([C@@H]1CCCN(C1)C(=O)N[C@H](CNC)CC1CCCCC1)c1cccc(Cl)c1

InChI Key InChIKey=NKSWZMBNAZQJQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305442   

TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305442((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-propiona...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305442((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-propiona...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed