BDBM50305445 (R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-(methylsulfonamido)butyl)-N-((S)-1-cyclohexyl-3-(methylamino)propan-2-yl)piperidine-1-carboxamide::CHEMBL592284

SMILES CNC[C@H](CC1CCCCC1)NC(=O)N1CCC[C@H](C1)[C@@](O)(CCCNS(C)(=O)=O)c1cccc(Cl)c1

InChI Key InChIKey=HNBRZLZXNNPMLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305445   

TargetRenin(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305445BDBM50305445((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-(methyls...)
Affinity DataIC50: 177nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed