BDBM50305628 CHEMBL589135::N-(2,4-dichlorobenzyl)-4-phenoxypiperidine-1-carboxamide

SMILES Clc1ccc(CNC(=O)N2CCC(CC2)Oc2ccccc2)c(Cl)c1

InChI Key InChIKey=GNYKLFXXXBPLNY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50305628   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305628(N-(2,4-dichlorobenzyl)-4-phenoxypiperidine-1-carbo...)
Affinity DataIC50: 4.30nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305628(N-(2,4-dichlorobenzyl)-4-phenoxypiperidine-1-carbo...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305628(N-(2,4-dichlorobenzyl)-4-phenoxypiperidine-1-carbo...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 2J2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305628(N-(2,4-dichlorobenzyl)-4-phenoxypiperidine-1-carbo...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 2J2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305628(N-(2,4-dichlorobenzyl)-4-phenoxypiperidine-1-carbo...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305628(N-(2,4-dichlorobenzyl)-4-phenoxypiperidine-1-carbo...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed