BDBM50305645 (3-(4-morpholino-7-(piperidin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)phenyl)methanol::CHEMBL595746

SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ccn(C3CCNCC3)c2n1

InChI Key InChIKey=IOBPQMXNKOPXNC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305645   

LigandPNGBDBM50305645((3-(4-morpholino-7-(piperidin-4-yl)-7H-pyrrolo[2,3...)
Affinity DataIC50: 26nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305645((3-(4-morpholino-7-(piperidin-4-yl)-7H-pyrrolo[2,3...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50305645((3-(4-morpholino-7-(piperidin-4-yl)-7H-pyrrolo[2,3...)
Affinity DataIC50: 510nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed