BDBM50305646 4-(6-morpholino-9H-purin-2-yl)phenol::CHEMBL592263

SMILES Oc1ccc(cc1)-c1nc(N2CCOCC2)c2[nH]cnc2n1

InChI Key InChIKey=PSGSPCJHCOUEEU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305646   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305646(4-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59226...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50305646(4-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59226...)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50305646(4-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59226...)
Affinity DataIC50: 8.56E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed