BDBM50305652 4-(2-(benzo[d][1,3]dioxol-5-yl)-9H-purin-6-yl)morpholine::CHEMBL593283

SMILES C1Oc2ccc(cc2O1)-c1nc(N2CCOCC2)c2[nH]cnc2n1

InChI Key InChIKey=HWVQDXXMHUAOHV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305652   

LigandPNGBDBM50305652(4-(2-(benzo[d][1,3]dioxol-5-yl)-9H-purin-6-yl)morp...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50305652(4-(2-(benzo[d][1,3]dioxol-5-yl)-9H-purin-6-yl)morp...)
Affinity DataIC50: 6.91E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305652(4-(2-(benzo[d][1,3]dioxol-5-yl)-9H-purin-6-yl)morp...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed