BDBM50305662 3-(9-((1-benzylpiperidin-4-yl)methyl)-6-morpholino-9H-purin-2-yl)phenol::CHEMBL590112

SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2ncn(CC3CCN(Cc4ccccc4)CC3)c2n1

InChI Key InChIKey=HGLYXSLZOIRAJP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305662   

LigandPNGBDBM50305662(3-(9-((1-benzylpiperidin-4-yl)methyl)-6-morpholino...)
Affinity DataIC50: 199nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305662(3-(9-((1-benzylpiperidin-4-yl)methyl)-6-morpholino...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
LigandPNGBDBM50305662(3-(9-((1-benzylpiperidin-4-yl)methyl)-6-morpholino...)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed