BDBM50306315 (R)-N-(4-(7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-yl)benzyl)-N-cyclobutylmethanesulfonamide::CHEMBL599282

SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccc(CN(C2CCC2)S(C)(=O)=O)cc1

InChI Key InChIKey=HEHKUMIGMLBRDW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306315   

TargetD(1A) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306315((R)-N-(4-(7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetr...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306315((R)-N-(4-(7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetr...)
Affinity DataKi:  5.90nMAssay Description:Binding affinity to dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306315((R)-N-(4-(7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetr...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306315((R)-N-(4-(7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetr...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed