BDBM50306498 CHEMBL600398::N-(4-(6,7-dimethoxyquinazolin-4-yloxy)-3-fluorophenyl)-4,4,4-trifluoro-3-(phenylamino)butanamide

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)CC(Nc4ccccc4)C(F)(F)F)cc3F)c2cc1OC

InChI Key InChIKey=JKCHAENVNKVZKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306498   

TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306498(N-(4-(6,7-dimethoxyquinazolin-4-yloxy)-3-fluorophe...)
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant GST-fused VEGFR2 expressed in baculovirus infected Sf9 cells by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306498(N-(4-(6,7-dimethoxyquinazolin-4-yloxy)-3-fluorophe...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant GST-fused c-Met expressed in baculovirus infected high five cells by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed