BDBM50306502 CHEMBL612137::N-(6-(2-fluoro-4-(1,1,1-trifluoro-4-oxo-4-(phenylamino)butan-2-ylamino)phenoxy)pyrimidin-4-yl)pyrrolidine-1-carboxamide

SMILES Fc1cc(NC(CC(=O)Nc2ccccc2)C(F)(F)F)ccc1Oc1cc(NC(=O)N2CCCC2)ncn1

InChI Key InChIKey=YKCBBFUAFHUPJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306502   

TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306502(N-(6-(2-fluoro-4-(1,1,1-trifluoro-4-oxo-4-(phenyla...)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant GST-fused VEGFR2 expressed in baculovirus infected Sf9 cells by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306502(N-(6-(2-fluoro-4-(1,1,1-trifluoro-4-oxo-4-(phenyla...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant GST-fused c-Met expressed in baculovirus infected high five cells by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed